Health
Amylyx’s ALS drug fails critical trial, causing stock price to plummet, ET HealthWorld reports
In a shocking development, Amylyx Pharmaceuticals is considering pulling its ALS treatment drug, Relyvrio, from the market after it failed to slow disease progression in a late-stage trial. The company’s shares plummeted by 85 percent in response to this news on Friday, prompting discussions with regulators about the future of the drug.
Amylyx Pharmaceuticals announced that it would cease promotions of Relyvrio and make a decision on its fate in the coming weeks. Co-CEO Justin Klee stated, “We will follow the science and will do what’s right for the community, which may include voluntarily removing the product from the market.” However, the drug will still be available for the time being.
Approved in September 2022 based on mid-stage trial data, Relyvrio was believed to slow disease progression and extend life expectancy. Nevertheless, the larger study involving 664 patients did not confirm these benefits, as no significant difference was observed between patients treated with the drug and those given a placebo.
Following the disappointing results, Amylyx’s shares tumbled by 82 percent, potentially wiping out over $1 billion from its market value if the losses persist. Despite generating sales of around $381 million in 2023, the drug’s future now hangs in the balance as the company evaluates its next steps.
People afflicted with ALS, a debilitating condition that causes progressive paralysis and is fatal, have limited treatment options, including Radicava by Mitsubishi Tanabe and the generic drug riluzole. The ALS Association expressed sadness over the news, acknowledging the impact on the ALS community, which comprises approximately 60,000 people in the U.S. and Europe.
- Viral10 months ago
Zoe Moore’s OnlyFans Content Leak Sparks Online Controversy
- Latest News10 months ago
Video of Xena the Witch’s Viral Flashing Incident on Jack Doherty and HeelMike Kick’s Live Stream
- Auto10 months ago
Kawasaki Introduces Special Offers of Up to ₹60,000: Full Details Here
- General10 months ago
Where Is Matt Shirvington Now? Is Matt Shirvington Leaving Sunrise?
- Viral10 months ago
Online Privacy Concerns Spike as Linnea Sky OnlyFans Content Leaks, Sparking Digital Frenzy
- Entertainment10 months ago
Umair Jaswal What Religion is Umair Jaswal? Is Umair Jaswal a Muslim?
- Sports6 months ago
2024 UFL Playoff Schedule, Picture, Dates, Times, and TV Coverage
- Entertainment8 months ago
Who is Ugly Sweater on the Masked Singer?
You must be logged in to post a comment Login